Spravato (esketamine)
At TMS of Austin, we are committed to offering cutting-edge treatments for individuals struggling with severe depression. Spravato® (esketamine) is an FDA-approved nasal spray designed specifically for people with treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts or actions.
If you or a loved one are struggling with treatment-resistant depression, schedule a consultation today to see if Spravato® is right for you.
A Breakthrough Treatment for Depression
For many patients, traditional antidepressants—such as SSRIs and SNRIs—can take weeks or even months to take full effect, and even then, they may not provide sufficient relief. Spravato® offers a revolutionary approach, working through a different mechanism in the brain than standard antidepressant medications.
Unlike conventional treatments, which primarily affect serotonin, norepinephrine, and dopamine, Spravato® targets the brain’s glutamate system—one of the most abundant neurotransmitters involved in mood regulation, memory, and cognitive function. This unique mechanism promotes rapid synaptic connections, helping to restore neural pathways that may be damaged due to prolonged depression.
For individuals who have not found relief through multiple antidepressants, Spravato® provides a new path forward, often delivering measurable symptom improvement in days or weeks, rather than months.
How Spravato® Works
Spravato® is a nasal spray medication administered at TMS of Austin in a safe, supervised clinical setting. It works differently from traditional antidepressants by restoring connections between brain cells, helping to improve mood and cognitive function.
Treatment Process:
Supervised Administration – Spravato® is taken under medical supervision at our clinic.
Observation Period – After administration, patients remain at the clinic for two hours for monitoring.
Treatment Schedule – Patients typically receive Spravato® twice a week for the first month, then gradually taper based on their progress.
Who is Eligible for Spravato®?
Spravato® is designed for individuals who:
✔ Have tried at least two antidepressant medications without sufficient improvement.
✔ Are diagnosed with treatment-resistant depression (TRD).
✔ Have major depressive disorder (MDD) with suicidal thoughts or actions.
A consultation with our specialists will determine if Spravato® is the right treatment for you.
Benefits of Spravato® Treatment
🌟 Rapid relief – Some patients experience improvements in symptoms within hours to days.
🌟 FDA-approved – Safe and clinically tested for depression.
🌟 Effective for TRD – Helps patients who have not responded to traditional antidepressants.
🌟 Supervised care – Always administered in a controlled medical setting.
What to Expect During Treatment
First Visit: Our medical team will review your medical history and assess your eligibility.
Ongoing Sessions: Spravato® is administered twice a week for the first four weeks, followed by a maintenance phase.
Comfort & Support: During each session, you’ll be monitored in a comfortable, private setting at our clinic.